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Our Science

With 25,000 clinical researchers testing every day and cutting-edge innovations, our science holds the cure.

Science Drives Everything

Revolutionary medicines enable us to enrich and extend life for people living with all types of diseases. Research and Development is at the heart of fulfilling Pfizer’s purpose worldwide as we work to translate advanced science and technologies into therapies that matter for patients in need.

Our Areas of Focus

We focus our efforts in six core areas where we are best positioned to develop medicines for much needed therapy areas.

Over the past decade, we’ve taken bold new approaches to translate scientific research into effective medicines for people living with cancer. Now, we’re working tirelessly to develop a new generation of breakthroughs across multiple cancers and tumor types.

There are over 7,000 known rare diseases that affect approximately 400 million people worldwide. 80% of these diseases have genetic origins and 50% affect children. Collectively, people living with a rare disease represent one of the largest underserved patient communities in the world, with only 5% of known rare diseases having one or more approved treatments.

Cardiovascular (heart) and metabolic diseases are the number one cause of death worldwide. We’re committed to addressing these global health challenges by developing potential therapies to treat or prevent disease progression and improve the quality of life for patients.

At Pfizer, we have a long history in vaccine research and development, including a pivotal role in the eradication of polio and smallpox. Through the development of innovative delivery systems and technologies (the term often used is “novel vaccines”), we’ve created innovations for preventing deadly bacterial infections like those caused by S. pneumoniae and N. meningitidis.

Inflammation is a critical response to potential danger signals and damage to organs in our body. But with autoimmune diseases such as rheumatoid arthritis, lupus, ulcerative colitis, Crohn’s disease, and many others, our own immune system turns against our organs. Many patients with chronic inflammatory diseases have access to therapies that only relieve their symptoms. We believe we can address the root cause of these debilitating diseases by treating it at the molecular level.

Infectious diseases continue to be one of the biggest public health concerns around the world. Since our pioneering work on penicillin in the 1940s, we have a strong history of addressing this evolving risk.

Our Areas of Innovation

Gene Therapy

Gene therapy is the next generation of medicine targeting the underlying cause of a genetic disease. It has the potential to offer patients a transformational clinical benefit and dramatically improve quality of life.

Learn More About Genes as Medicine, Their Promise, and Manufacturing (English)

Medicinal Science

We’re investing in next-generation science and technology to invent tomorrow’s innovative therapies. The breadth and depth of our colleagues’ technical expertise is second to none, and underpins our groundbreaking approach to the discovery and development of medicines and vaccines

Learn More About Our Cutting-Edge Medicinal Sciences Research (English)

Precision Medicine

Precision medicine is not only a focus of our R&D strategy, but a philosophy that guides everything we do. New technology platforms enable us to fulfill their potential through cutting-edge applications that better understand the biological basis of a disease.

Learn More About The Potential of Precision Medicine (English)

Maternal Immunization

Leveraging years of scientific expertise, we’re at the forefront of this field, working tirelessly to discover and develop vaccines that would protect young infants around the world from disease through maternal immunization

Learn More About Advancing Vaccine Science with Maternal Immunization (English)

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News Careers Contact Pfizer Global

Pfizer Laboratories (Pty) Ltd. Company Reg. No. 1954/000781/07. Building 2, 1st Floor, Maxwell Office Park, Magwa Crescent, Waterfall City,

Midrand, Johannesburg, South Africa. Tel. No: 0860 PFIZER (734937).